Background. The bio element nutritional status may be defined as deficient, adequate, or excessive/toxic. Non-invasive method of hair collection makes it a tissue of choice for multi bio element analysis in precision medicine and nutritional epidemiology. Methods. Hair multi bio element profile of healthy 1073 subjects (339 Men. 734Women) was analyzed with the ICP MS. The frequency distribution of the hair log concentration data was used to assess the bio element nutritional status with the median derivatives bioassay. The assay allows for the reliable assessment of the bio element deficiency, adequacy, and excess. Results. Nutritional status of P, Zn, and the bio element pairs of I and Se, Ca and Mg, and Na and K are fully exposed and illustrated. The nutritional status of all twenty two hair bio elements are presented in Table 1 in their decreasing order of abundance (µg•g-1): Calcium, Zinc, Phosphorus, Sodium, Potassium, Magnesium, Silicon, Copper, Iron, Aluminum, Boron, Strontium, Chromium, Iodine, Selenium, and in (ng•g-1) for Nickel, Manganese, Molybdenum, Silver, Lithium, Cobalt and Gold. Conclusion. Hair bio element median derivatives bioassay proved to be a rapid, reliable, accurate, and fully reproducible method for assessing the bio element nutritional status, the nutritional health surveillance, and maintenance in precision medicine.
| Published in | American Journal of Biomedical and Life Sciences (Volume 11, Issue 1) |
| DOI | 10.11648/j.ajbls.20231101.11 |
| Page(s) | 1-14 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2023. Published by Science Publishing Group |
Hair, Essentialbio Elements, Entanglement, Interactions, Median Derivatives Bioassay, Reference Standards, Reliability, Nutritional Status
| [1] | The Merriam Webster Pocket Dictionary. Pocket Books Inc. New York 1947 p. 205. |
| [2] | Shetty P. Malnutrition and under nutrition. Medicine. 2003; 31: 18–22. |
| [3] | Hayes AW Principles and methods of toxicology, 4th Ed., Taylor and Francis, Philadelphia, PA, 2001. |
| [4] | Momčilović B, Reeves PG, Blake MJ. Idiorrhythmic dose-rate variability in dietary zinc intake generates different response pattern of zinc metabolism than conventional dose- response feeding. Brit. J. Nutr. 1997; 78: 173-191. |
| [5] | Momčilović B, Prejac J, Mimica N. In search of decoding the syntax of the bioelements in human hair. A critical overview, JTEMB 2017; 49: 1-11. |
| [6] | Harpley FW, Stewart GA, Young PA. Principles of biological assay. In International Encyclopedia of Pharmaceutical sciences and Therapeutics (Delanouis AL Ed.), Vpl. 1, Pergamum Press, Oxford 1973. |
| [7] | Chittleborough G. A chemist’s view of the analysis of human hair for trace elements. Sci. Total Environ. 1980; 14: 63-75. |
| [8] | Momčilović B. Lykken GI, Tao L, Wielopoloski L. Comparative analysis of 65Zn and 40K in human urine by library least square and window methods using a personal computer. J Radioanalyt Nucl Chem 1995; 195: 315-319. |
| [9] | Dinh K, Wang Q. A probabilistic Boolean model on hair follicle cell fate regulation by TGF-β. Biophysical Journal 2022; 121: 1-15. |
| [10] | Alpers DA, Bier DM, Carpenter KJ, McCormick DB, Miller AB, Jacques PF. History and impact of nutritional epidemiology. Adv Nutr 2014, doi: 10.3945/an.113.006353. |
| [11] | Finey AJ. Probit analysis. A statistical treatment of the sigmoid response curve, 2nd Ed. Cambridge Univ Press, Cambridge, UK 1952. |
| [12] | Momčilović B.: "Dietary zinc dose-rate idiorrhythm is a powerful tool for detection of subtle mineral interactions. A case for the expression of Recommended Dietary Allowances (RDA's) and Safety Limits (RfD) in the range format", Trace Elements in Man and Animals 9 (Fischer PW, LÁbbe MR, Cockell KA, Gibson RA, eds.), NRC Research Press, Ottawa, Canada, 1997; 9: 403-405. |
| [13] | Linder MC. Nutritional biochemistry and metabolism. Elsevier, Amsterdam, Netherland 1985. |
| [14] | DiPietro ES, Phillips DL. Paschal DC, Beese JW. Determination of trace elements in human hair, Biological Trace FElement Research 1989; 22: 83-100. |
| [15] | Braverman LE, Utiger RD (Eds.). Werner &Ingbar’s thyroid. A fundamental and clinical text, 9th. Ed, Lippincott Williams & Wilkins, Philadelphia, PA 2005. |
| [16] | Preedy VR, Burrow GN, Watson RR (Eds.). The comprehensive handbook of iodine. Nutritional biochemical, pathological and therapeutic aspects, Academic Press (imprint of Elsevier), Amsterdam, Netherlands 2009. |
| [17] | Prejac J, Morović S,, Drmić S, Morović J, Pisl Z, Momčilović B. New way to assess the bioelement selenium nutritional status non-invasively in vivo, Trace Elements in Medicine, 2022; 23 (2): 6-15. |
| [18] | Skalny AV, Burtseva T, Salnikova EV, Ajsuvakova OP, Skalnaya MG, Kirichuk AA, Tinkova Geographic variation of environmental, food, and human hair selenium content in an industrial region of Russia. Environ Res 2019; 171: 293-301. |
| [19] | amburo E, Varrica D, Dongarra G. Coverage intervals for trace elements in human scalp hair are [geographic] site specific. Environ Toxicol Pharmacol 2015; 19: 70-76. |
| [20] | Strazzullo P, Leclercq C. Sodium, Adv. Nutr 2014; 5: 188-190. |
| [21] | Traber MG, Manor D. Potassium, Adv Nutr 2012; 3: 820-821. |
| [22] | Momčilović B, Prejac J, Višnjević V, Drmić S, Mimica N, Bukovec-Megle Ž, Brundić S, Skalny AV. The muscle immobility of depression-The weightlessness within, Psychology 2012; 3: 825- 833. |
| [23] | Momčilović B, Dietary salt in the whirl of nutritional science, public health and food processing industry, Trace elements in Medicine 2021; 22 (4): 3-13. |
| [24] | Langappa VR, Farttarey K. Physiological Medicine, A clinical approach to basic medical physiology, McGrew Hill, New York, NY 2000. |
| [25] | Sperelakis N. Regulation of ionic channels by phosphorylation, in Cell physiology. Source book, Ch. 32, Academic Press, San Diego, CA, `1998: 499=509. |
| [26] | Momčilović B. Case HR 0101 144 Increased hair K/Na ratio in cystic fibrosis, Trace elements in medicine, 2021; 22 (3): 58-59. |
| [27] | Weawer CM, Heaney RR. Calcium, in Modern Nutrition in health and disease (Shills ME, Shike M, Ross AC, Caballero B, Cousins RJ, Eds) m 10th Ed., Lippincott Williams & Wilkins, Philadelphia, PA 2006: 194-210. |
| [28] | Rude RK, Shils ME. Magnesium. in Modern Nutrition in health and disease (Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ, Eds), in 0th Ed., Lippincott Williams & Wilkins, Philadelphia, PA 2006: 223-247. |
| [29] | Smith R Disorders of the skeleton, in Conscience Oxford Textbook of Medicine (Ledingham JGG, Warnell, Eds.), Section 9, Oxford Univ Press, Oxford, UK 2000: 941-965. |
| [30] | Kanis JA. Disorders of calcium metabolism,. Disorders of the skeleton, in Conscience Oxford Textbook of Medicine (Ledingham JGG, Warnell, Eds.), Ch. 7.5, Oxford Univ Press, Oxford, UK 2000: 839-850. |
| [31] | Porto de Silveira CL, Mikeley L, de Ca\rrvalho Portes L<. de Paula FA. A; la; ime earth element and phosphorus anomalies in human hair samples asd an indicator for osteoporosis, Fifyh COMTOX Sym; posium in Toxicology and Clinical Chemistry of Metals, Vancouver, Canada, Abstract 311, 1995. |
| [32] | Selye H. Calciphylaxis, Chicago Univ Press, Chichago, IL 1962. |
| [33] | WHO and FAO (UN)/ Vitamin and mineral requirements to human nutrition, 2nd Ed., World Health Organization and Food and Agriculture Organization of the United Nation Geneva, Switzerland 2004. |
| [34] | Momčilović B, Handl S, Zjai V. A case of alopecia in man associated with zinc deficiency, Trace Element Metabolism in Man and Animals 4 (J. McC. Howell, J. M. Gawthorne, C. L. White, eds.). Austral Acad Sci, Canberra 1981; 4: 491-494. |
| [35] | Momčilović B (Plenary Lecture). The epistemology of trace element balance and interaction, Plenary Lecture. Trace Elements in Man and Animals 6 (L. S. Hurley, C. L. Keen, B. Lonnerdal, R. B. Rucker, eds.). Plenum Publ Co, NY 1988; 6: 173-177. |
| [36] | Momilovi B. Low serum copper in urticaria and post virus B hepatitis, 7th International Symposium on Trace Elements in Man and Animals (TEMA 7). Dubrovnik 1990; 7: 23. |
| [37] | Prejac J, Skalny AV, Grabeklis AR, Uzum S, Mimica N, Momčilović B. Assessing the boron nutritional status by analyzing its cumulative frequency distribution in the hair and whole blood, J Trace Element Med Biol, 3018; 45: 50-56. |
| [38] | Guy RH, Hostynek JJ, Hunz RS, Lorence CR. Metals and the skin. Topical effects and systematic absorption. Marcel Dekker Inc., New York 1999. |
| [39] | Momčilović B.: "A case report of acute human molybdenum toxicity from a dietary molybdenum supplement - A new member of the “lucor metallicum” family, Arh.hig.rada toksikol 1999; 50: 289-297. |
| [40] | Momčilović B, Prejac J, Ivičić N. Trace element fingerprint of human depression, Trace Elements and Electrolytes, 2007; 25: 225 (Abstract). |
| [41] | Mimica N, Prejac J, Skalny AV, Grabeklis AR, Momčilović B. Assessing the lithium nutritional status by analyzing its cumulative frequency distribution in the hair and whole blood, J Trace Element Med Biol, 3017; 44: 46. |
| [42] | Momčilović B, Kostial K. Kinetics of lead retention and distribution in suckling and aduly rays, Environ Res 1974; 8: 214-220. |
| [43] | Lykken GI, Ward T, Momčilopvić B, Traudt J. Analysis of human tissues, including brain, containing environmental toxic metal-tagged cp, bustion particulate matter PM 2,5, Academia Letters 2021, Article 4212. https://doi.org/10.20936/ALA212. |
APA Style
Momcilovic Berislav, Morovic Sandra, Morovic Jadran. (2023). My Hair Guides My Bioelement Dietary Requirements. American Journal of Biomedical and Life Sciences, 11(1), 1-14. https://doi.org/10.11648/j.ajbls.20231101.11
ACS Style
Momcilovic Berislav; Morovic Sandra; Morovic Jadran. My Hair Guides My Bioelement Dietary Requirements. Am. J. Biomed. Life Sci. 2023, 11(1), 1-14. doi: 10.11648/j.ajbls.20231101.11
AMA Style
Momcilovic Berislav, Morovic Sandra, Morovic Jadran. My Hair Guides My Bioelement Dietary Requirements. Am J Biomed Life Sci. 2023;11(1):1-14. doi: 10.11648/j.ajbls.20231101.11
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Download@article{10.11648/j.ajbls.20231101.11,
author = {Momcilovic Berislav and Morovic Sandra and Morovic Jadran},
title = {My Hair Guides My Bioelement Dietary Requirements},
journal = {American Journal of Biomedical and Life Sciences},
volume = {11},
number = {1},
pages = {1-14},
doi = {10.11648/j.ajbls.20231101.11},
url = {https://doi.org/10.11648/j.ajbls.20231101.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20231101.11},
abstract = {Background. The bio element nutritional status may be defined as deficient, adequate, or excessive/toxic. Non-invasive method of hair collection makes it a tissue of choice for multi bio element analysis in precision medicine and nutritional epidemiology. Methods. Hair multi bio element profile of healthy 1073 subjects (339 Men. 734Women) was analyzed with the ICP MS. The frequency distribution of the hair log concentration data was used to assess the bio element nutritional status with the median derivatives bioassay. The assay allows for the reliable assessment of the bio element deficiency, adequacy, and excess. Results. Nutritional status of P, Zn, and the bio element pairs of I and Se, Ca and Mg, and Na and K are fully exposed and illustrated. The nutritional status of all twenty two hair bio elements are presented in Table 1 in their decreasing order of abundance (µg•g-1): Calcium, Zinc, Phosphorus, Sodium, Potassium, Magnesium, Silicon, Copper, Iron, Aluminum, Boron, Strontium, Chromium, Iodine, Selenium, and in (ng•g-1) for Nickel, Manganese, Molybdenum, Silver, Lithium, Cobalt and Gold. Conclusion. Hair bio element median derivatives bioassay proved to be a rapid, reliable, accurate, and fully reproducible method for assessing the bio element nutritional status, the nutritional health surveillance, and maintenance in precision medicine.},
year = {2023}
}
TY - JOUR T1 - My Hair Guides My Bioelement Dietary Requirements AU - Momcilovic Berislav AU - Morovic Sandra AU - Morovic Jadran Y1 - 2023/02/04 PY - 2023 N1 - https://doi.org/10.11648/j.ajbls.20231101.11 DO - 10.11648/j.ajbls.20231101.11 T2 - American Journal of Biomedical and Life Sciences JF - American Journal of Biomedical and Life Sciences JO - American Journal of Biomedical and Life Sciences SP - 1 EP - 14 PB - Science Publishing Group SN - 2330-880X UR - https://doi.org/10.11648/j.ajbls.20231101.11 AB - Background. The bio element nutritional status may be defined as deficient, adequate, or excessive/toxic. Non-invasive method of hair collection makes it a tissue of choice for multi bio element analysis in precision medicine and nutritional epidemiology. Methods. Hair multi bio element profile of healthy 1073 subjects (339 Men. 734Women) was analyzed with the ICP MS. The frequency distribution of the hair log concentration data was used to assess the bio element nutritional status with the median derivatives bioassay. The assay allows for the reliable assessment of the bio element deficiency, adequacy, and excess. Results. Nutritional status of P, Zn, and the bio element pairs of I and Se, Ca and Mg, and Na and K are fully exposed and illustrated. The nutritional status of all twenty two hair bio elements are presented in Table 1 in their decreasing order of abundance (µg•g-1): Calcium, Zinc, Phosphorus, Sodium, Potassium, Magnesium, Silicon, Copper, Iron, Aluminum, Boron, Strontium, Chromium, Iodine, Selenium, and in (ng•g-1) for Nickel, Manganese, Molybdenum, Silver, Lithium, Cobalt and Gold. Conclusion. Hair bio element median derivatives bioassay proved to be a rapid, reliable, accurate, and fully reproducible method for assessing the bio element nutritional status, the nutritional health surveillance, and maintenance in precision medicine. VL - 11 IS - 1 ER -
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