Background: The correlation between symptomatic knee osteoarthritis (OA) and whole blood cell count (CBC) has not been well studied based on large-scale population. The purpose of this study was to analyze its correlation with serological examination, especially with CBC tests. Methods: Samples in our study was derived from China Health and Retirement Longitudinal Study (CHARLS), wave 3. Blood samples from 13,420 participants were collected. We define a subject as symptomatic knee OA patient if both questions (Individuals were asked whether they were troubled with knee pain and had a doctor-diagnosed arthritis) were responded positively. A total of 12,952 individuals were classified into four groups. Post hoc multiple comparisons were conducted then. The criterion of significance is p<0.05. Results: Among the 20967 people included in the analysis, 19692 answered the diagnosis questions. Our results showed that the prevalence of symptomatic knee OA was 9.18%. The level of hemoglobin (Hgb) (13.34±1.80 g/dl) in patients with symptomatic knee OA was significantly lower than that in other individuals. The HCT level of symptomatic knee OA individuals (40.53±5.32%) was significantly lower than that of other individuals. Patients with arthritis but without ongoing knee pain had the lowest PLT level (199.09±76.88 × 109/L) when compared with other groups. Conclusion: symptomatic knee osteoarthritis is common in China. Patients with symptomatic knee OA showed a downward trend in the serological results of hemoglobin and hematocrit compared with other populations. More research on symptomatic knee osteoarthritis needs to be carried out.
Published in | Journal of Surgery (Volume 10, Issue 2) |
DOI | 10.11648/j.js.20221002.16 |
Page(s) | 78-82 |
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2022. Published by Science Publishing Group |
Symptomatic Knee Osteoarthritis, Prevalence, Peripheral Blood, Correlation
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APA Style
Tongyi Zhang, Yudian Qiu, Jianhao Lin, Nan Min, Yaonan Zhang, et al. (2022). Correlation Between Symptomatic Knee Osteoarthritis and Serological Examination: A Longitudinal Study in China. Journal of Surgery, 10(2), 78-82. https://doi.org/10.11648/j.js.20221002.16
ACS Style
Tongyi Zhang; Yudian Qiu; Jianhao Lin; Nan Min; Yaonan Zhang, et al. Correlation Between Symptomatic Knee Osteoarthritis and Serological Examination: A Longitudinal Study in China. J. Surg. 2022, 10(2), 78-82. doi: 10.11648/j.js.20221002.16
AMA Style
Tongyi Zhang, Yudian Qiu, Jianhao Lin, Nan Min, Yaonan Zhang, et al. Correlation Between Symptomatic Knee Osteoarthritis and Serological Examination: A Longitudinal Study in China. J Surg. 2022;10(2):78-82. doi: 10.11648/j.js.20221002.16
@article{10.11648/j.js.20221002.16, author = {Tongyi Zhang and Yudian Qiu and Jianhao Lin and Nan Min and Yaonan Zhang and Qingyun Xue and Qiang Wang and Liangyuan Wen}, title = {Correlation Between Symptomatic Knee Osteoarthritis and Serological Examination: A Longitudinal Study in China}, journal = {Journal of Surgery}, volume = {10}, number = {2}, pages = {78-82}, doi = {10.11648/j.js.20221002.16}, url = {https://doi.org/10.11648/j.js.20221002.16}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20221002.16}, abstract = {Background: The correlation between symptomatic knee osteoarthritis (OA) and whole blood cell count (CBC) has not been well studied based on large-scale population. The purpose of this study was to analyze its correlation with serological examination, especially with CBC tests. Methods: Samples in our study was derived from China Health and Retirement Longitudinal Study (CHARLS), wave 3. Blood samples from 13,420 participants were collected. We define a subject as symptomatic knee OA patient if both questions (Individuals were asked whether they were troubled with knee pain and had a doctor-diagnosed arthritis) were responded positively. A total of 12,952 individuals were classified into four groups. Post hoc multiple comparisons were conducted then. The criterion of significance is pResults: Among the 20967 people included in the analysis, 19692 answered the diagnosis questions. Our results showed that the prevalence of symptomatic knee OA was 9.18%. The level of hemoglobin (Hgb) (13.34±1.80 g/dl) in patients with symptomatic knee OA was significantly lower than that in other individuals. The HCT level of symptomatic knee OA individuals (40.53±5.32%) was significantly lower than that of other individuals. Patients with arthritis but without ongoing knee pain had the lowest PLT level (199.09±76.88 × 109/L) when compared with other groups. Conclusion: symptomatic knee osteoarthritis is common in China. Patients with symptomatic knee OA showed a downward trend in the serological results of hemoglobin and hematocrit compared with other populations. More research on symptomatic knee osteoarthritis needs to be carried out.}, year = {2022} }
TY - JOUR T1 - Correlation Between Symptomatic Knee Osteoarthritis and Serological Examination: A Longitudinal Study in China AU - Tongyi Zhang AU - Yudian Qiu AU - Jianhao Lin AU - Nan Min AU - Yaonan Zhang AU - Qingyun Xue AU - Qiang Wang AU - Liangyuan Wen Y1 - 2022/03/23 PY - 2022 N1 - https://doi.org/10.11648/j.js.20221002.16 DO - 10.11648/j.js.20221002.16 T2 - Journal of Surgery JF - Journal of Surgery JO - Journal of Surgery SP - 78 EP - 82 PB - Science Publishing Group SN - 2330-0930 UR - https://doi.org/10.11648/j.js.20221002.16 AB - Background: The correlation between symptomatic knee osteoarthritis (OA) and whole blood cell count (CBC) has not been well studied based on large-scale population. The purpose of this study was to analyze its correlation with serological examination, especially with CBC tests. Methods: Samples in our study was derived from China Health and Retirement Longitudinal Study (CHARLS), wave 3. Blood samples from 13,420 participants were collected. We define a subject as symptomatic knee OA patient if both questions (Individuals were asked whether they were troubled with knee pain and had a doctor-diagnosed arthritis) were responded positively. A total of 12,952 individuals were classified into four groups. Post hoc multiple comparisons were conducted then. The criterion of significance is pResults: Among the 20967 people included in the analysis, 19692 answered the diagnosis questions. Our results showed that the prevalence of symptomatic knee OA was 9.18%. The level of hemoglobin (Hgb) (13.34±1.80 g/dl) in patients with symptomatic knee OA was significantly lower than that in other individuals. The HCT level of symptomatic knee OA individuals (40.53±5.32%) was significantly lower than that of other individuals. Patients with arthritis but without ongoing knee pain had the lowest PLT level (199.09±76.88 × 109/L) when compared with other groups. Conclusion: symptomatic knee osteoarthritis is common in China. Patients with symptomatic knee OA showed a downward trend in the serological results of hemoglobin and hematocrit compared with other populations. More research on symptomatic knee osteoarthritis needs to be carried out. VL - 10 IS - 2 ER -